Posted in breast, cancer, Health, news

October is Breast Cancer Awareness Month

ABOVE:  DR. DALIAH UNDERGOING A 3-D MAMMOGRAM TO SCREEN FOR BREAST CANCER

 

Celebrities such as Julia Louise-Dreyfus, Olivia Newton-John, Christina Applegate and Cynthia Nixon have revealed their breast cancer diagnoses, helping raise awareness for the most common cancer to affect women.  It’s the second most common cause of cancer death in females.

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#SHIRTSOFF #BREASTCANCERAWARENESSMONTH

 

How common is breast cancer?

1 in 8 women will develop invasive breast cancer over the course of their lifetime. According to the American Cancer Society, an estimated 268,000 cases of invasive breast cancer are expected to be diagnosed in women in the US with 63,000 cases of non-invasive breast cancer, a rise from last year.

41,700 women and 500 men are expected to die this year of breast cancer.

 

What are the risk factors for breast cancer?

Risk factors for breast cancer include:

  • Age greater than 50
  • Family History
  • BRAC1 and BRAC2 genetic mutations
  • Alcohol use
  • Never been pregnant or becoming pregnant for the first time over 35 years old
  • Early menarche at age 11 or younger
  • Obesity, especially after menopause
  • Dense breasts
  • Lack of physical activity
  • Use of oral contraceptives
  • Previous “precancerous” tumors such as atypical hyperplasia
  • DES exposure
  • Previous radiation therapy

How is breast cancer staged?

Breast cancer is staged based on size of the tumor, if lymph nodes are affected and whether the cancer has spread to distant areas of the body.  Prognosis varies greatly on the stage.

 

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IMAGE ABOVE FROM JOHNSTON HEALTH

 

Is family history a huge factor?

85% of breast cancer cases occur in women with NO family history.

 

Screening of breast cancer

Mammograms are the first line screening tool for breast cancer and are currently recommended biennial for women aged 50-74.  However for those at higher risk, mammogram screening should start earlier, with possible follow-up ultrasound, and be performed more regularly.

 

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3-D MAMMOGRAM IMAGE

 

Daliah Wachs, MD, FAAFP is a nationally syndicated radio personality on GCN Network, KDWN, and iHeart Radio.

Posted in cancer, Health, medications, news

Ranitidine Being Evaluated For Cancer Causing Chemical

The FDA has announced that samples of ranitidine, an H2 Blocker used for stomach upset, reflux and ulcers sold generically and under the brand name of Zantac, were found to have the contaminant N-nitrosodimethylamine (NDMA).  This is one of the chemicals that prompted the generic ARB blood pressure medication recalls last year.

There have been no reports of users becoming ill and no recall has been suggested at this time. In animals, NDMA is known to cause liver and lung cancer.  In humans its carcinogenic risk is unknown, however the CDC states it may cause liver function impairment and cirrhosis.

The FDA writes:

The FDA is not calling for individuals to stop taking ranitidine at this time; however, patients taking prescription ranitidine who wish to discontinue use should talk to their health care professional about other treatment options. People taking OTC ranitidine could consider using other OTC medicines approved for their condition. There are multiple drugs on the market that are approved for the same or similar uses as ranitidine.
Consumers and health care professionals should report any adverse reactions with ranitidine to the FDA’s MedWatch program to help the agency better understand the scope of the problem:

The investigation is ongoing and more needs to be looked at when it comes to this manufacturing process suspected to result in these “impurities” being made.

Last year NDEA was also found in the generic  blood pressure medications that were the subject of recall, however has not yet been suggested as being being present in ranitidine.

N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) was the third chemical detected resulting in the latest two recalls of losartan, an angiotensin receptor blocker commonly used to treat hypertension (high blood pressure).  It is believed to have been created during the manufacturing process of the generic drug.

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NMBA, according to Toronto Research Chemicals, is a known carcinogen in a wide range of animal species.

Last Fall, ScieGen Pharmaceuticals, Inc. recalled certain lots of irbesartan, a similar angiotensin receptor blocker used in blood pressure management.

The recalls initially began last summer when FDA recalled a number of lots of valsartan due to an “impurity”, N-nitrosodimethylamine (NDMA) that is known to cause cancer in animals.  Weeks later they additionally found traces of N-nitrosodiethylamine (NDEA).

According to Reuters, earlier last summer, the MHRA, Medicines and Healthcare Products Regulatory Agency, located in the UK, said the appearance of the impurity, N-nitrosodimethylamine (NDMA), came after a change in the process for making valsartan at one facility owned by Zhejiang Huahai Pharmaceuticals, a company in Linhai, China.

With NDEA, data is limited, but due to its classification as a nitrosamine and its prevalence in tobacco smoke it is classified as a probable human carcinogen.

According to New Jersey Department of Health’s website, NDEA has been linked to liver, lung and gastrointestinal tract cancer in animals.

Losartan, valsartan and irbesartan are medications in the class of angiotensin receptor blockers (ARBs) used for high blood pressure and congestive heart failure.

Those taking either tablet for their blood pressure are urged to not abruptly stop their medication but rather check with their medical provider and pharmacy to see if their particular prescription is involved in the recall.

I suspect more recalls will follow as processes may be similar across multiple pharmaceutical facilities and NMBA, NDMA and NDEA are byproducts that may not be individually unique to just one “brand” of medication manufacturing.

 

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Great Gift!!!

The Ultimate Medical Student HandBook

 

Daliah Wachs, MD, FAAFP is a nationally syndicated radio personality on GCN Network, KDWN, and iHeart Radio.

Posted in cancer, Entertainment, Health, news

Eddie Money Dies at Age 70 After Battling Esophageal Cancer

70 year-old music legend, Edward Mahoney “Eddie Money”, who last month revealed in a video released by his realty TV series “Real Money” that he had stage 4 esophageal cancer, has sadly passed.

Per Variety: A statement provided by his family reads: “The Money Family regrets to announce that Eddie passed away peacefully early this morning. It is with heavy hearts that we say goodbye to our loving husband and father. We cannot imagine our world without him. We are grateful that he will live on forever through his music.”

 

He recently underwent heart valve surgery and reports say he also battled pneumonia.

Despite the cancer having had spread to his liver, lymph nodes and stomach, he appeared optimistic in a recent interview saying cancer has come a long way since the 1950’s and 60’s and “everyday above ground is a good day.”

What is esophageal cancer?

Esophageal cancer can occur anywhere along the gullet/food pipe.  There are different types such as adenocarcinoma (lower portion near the stomach), more commonly seen in Caucasians, and squamous cell carcinoma (middle to upper esophagus) more commonly seen in African Americans.  It’s the 6th common cause of cancer death worldwide and comprises 1% of all cancers diagnosed in the US.

According to the American Cancer Society, estimates for 2019 include:

  • ABOUT 17,650 NEW ESOPHAGEAL CANCER CASES DIAGNOSED (13,750 IN MEN AND 3,900 IN WOMEN)
  • ABOUT 16,080 DEATHS FROM ESOPHAGEAL CANCER (13,020 IN MEN AND 3,060 IN WOMEN)

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What are the symptoms of esophageal cancer?

Early esophageal cancer may not exhibit any signs. However if it progresses, symptoms may include any of the following:

  • abdominal pain
  • heartburn
  • feeling full despite not eating
  • nausea
  • vomiting blood
  • weight loss
  • loss of appetite
  • chest pain
  • cough

 

What are the risk factors for esophageal cancer?

Although esophageal cancer appears to afflict men more than women, risk factors  include:

  • Smoking
  • Alcohol use
  • Frequent imbibing of hot liquids
  • Obesity
  • Chronic GERD or heartburn that may have led to esophagus lining changes such as Barrett’s Esophagus disease
  • Vitamin deficiency
  • Drinking liquids that contain lye, an alkaline  chemical present in many soaps
  • Prior radiation to the chest

 

What is the prognosis of esophageal cancer?

If caught early and localized, the 5-year survival rate is over 45%. However, if it has spread, the 5 year survival rate can range any where from 5-20%.

 

How is esophageal cancer treated?

There are a variety of treatments for esophageal cancer including surgery, chemotherapy and radiation.

 

ultimate book cover final

Great Gift!!!

The Ultimate Medical Student HandBook

 

Daliah Wachs, MD, FAAFP is a nationally syndicated radio personality on GCN Network, KDWN, and iHeart Radio.

Posted in cancer, Health, news, Sports

Golden Knights Shea Theodore Reveals He Has Testicular Cancer

The 24 year old defenseman for the Golden Knights is recovering from surgery after being diagnosed with testicular cancer.

Shea Theodore in a story in the Player’s Tribune stated that during routine screening an hCG hormone test came up positive which commonly is seen in pregnant women, but could also be a sign of testicular cancer. This triggered his doctors to look for an abnormality.  A testicular ultrasound confirmed a 5mm X 5 mm lump, half the size of a pencil eraser and was set up for surgery.

He writes:

After the surgery, when the doctors were able to do a biopsy on the mass in my testicle, they found that it was a mixed germ cell tumor: embryonal and seminoma, stage I. While the embryonal component can be very aggressive and spread to abdominal lymph nodes, mine was caught early because of the comprehensive blood testing they conduct at the Worlds. 

Stage I testicular cancer (not spread beyond the testicles), found early has a 99% survival rate after 5 years.

This is a developing story…..

 

Testicular cancer is the most common type of cancer to affect young men, aged 15-44.

Yet the USPSTF has reviewed the evidence for screening for testicular cancer and has recommended AGAINST routine screening.

However, many medical providers still urge young men to do self testicular checks monthly.

Symptoms of testicular cancer may include any of the following:

  • Testicular lump
  • Testicular pain or heaviness
  • Testicular swelling
  • Numbness or tingling in the area of the testicle
  • Breast swelling
  • Back pain
  • Abdominal or groin pain
  • and more

 

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The earlier testicular cancer is found, the higher the survival rate.  This year, cancer.net predicts 9,310 men will be diagnosed with testicular cancer in the US.

 

 

 

 

Daliah Wachs, MD, FAAFP is a nationally syndicated radio personality on GCN Network, KDWN, and iHeart Radio.

Posted in cancer, Entertainment, Health, news

Eddie Money Reveals He Is Battling Advanced Esophageal Cancer

70 year-old music legend, Edward Mahoney “Eddie Money”, revealed in a video released by his realty TV series “Real Money” that he has stage 4 esophageal cancer.

The episode airs on AXS TV on September 12 and discusses how he went in for a routine screen when he was diagnosed.

He recently underwent heart valve surgery and reports say he also battled pneumonia.

Despite the cancer having spread to his liver, lymph nodes and stomach, he appears optimistic saying cancer has come a long way since the 1950’s and 60’s and “everyday above ground is a good day.”

What is esophageal cancer?

Esophageal cancer can occur anywhere along the gullet/food pipe.  There are different types such as adenocarcinoma (lower portion near the stomach), more commonly seen in Caucasians, and squamous cell carcinoma (middle to upper esophagus) more commonly seen in African Americans.  It’s the 6th common cause of cancer death worldwide and comprises 1% of all cancers diagnosed in the US.

According to the American Cancer Society, estimates for 2019 include:

  • About 17,650 new esophageal cancer cases diagnosed (13,750 in men and 3,900 in women)
  • About 16,080 deaths from esophageal cancer (13,020 in men and 3,060 in women)

a-medical-illustration-of-esophageal-cancer-original.jpg

 

What are the symptoms of esophageal cancer?

Early esophageal cancer may not exhibit any signs. However if it progresses, symptoms may include any of the following:

  • abdominal pain
  • heartburn
  • feeling full despite not eating
  • nausea
  • vomiting blood
  • weight loss
  • loss of appetite
  • chest pain
  • cough

 

What are the risk factors for esophageal cancer?

Although esophageal cancer appears to afflict men more than women, risk factors  include:

  • Smoking
  • Alcohol use
  • Frequent imbibing of hot liquids
  • Obesity
  • Chronic GERD or heartburn that may have led to esophagus lining changes such as Barrett’s Esophagus disease
  • Vitamin deficiency
  • Drinking liquids that contain lye, an alkaline  chemical present in many soaps
  • Prior radiation to the chest

 

What is the prognosis of esophageal cancer?

If caught early and localized, the 5-year survival rate is over 45%. However, if it has spread, the 5 year survival rate can range any where from 5-20%.

 

How is esophageal cancer treated?

There are a variety of treatments for esophageal cancer including surgery, chemotherapy and radiation.

 

ultimate book cover final

Great Gift!!!

The Ultimate Medical Student HandBook

 

Daliah Wachs, MD, FAAFP is a nationally syndicated radio personality on GCN Network, KDWN, and iHeart Radio.

 

 

 

 

 

Posted in cancer, Health, news, Politics

Supreme Court Justice Ruth Bader Ginsburg Undergoes Additional Pancreatic Cancer Treatment

Ruth Bader Ginsburg reportedly has undergone pancreatic cancer treatment and is doing well.

The radiation treatment took place at Memorial Sloan Kettering Cancer Center and began earlier this month when doctors found a tumor on her pancreas.

A statement from the Supreme Court reads:

Justice Ruth Bader Ginsburg today completed a three-week course of stereotactic ablative radiation therapy at Memorial Sloan Kettering Cancer Center in New York City. The focused radiation treatment began on August 5 and was administered on an outpatient basis to treat a tumor on her pancreas. The abnormality was first detected after a routine blood test in early July, and a biopsy performed on July 31 at Sloan Kettering confirmed a localized malignant tumor. As part of her treatment, a bile duct stent was placed. The Justice tolerated treatment well. She cancelled her annual summer visit to Santa Fe, but has otherwise maintained an active schedule. The tumor was treated definitively and there is no evidence of disease elsewhere in the body. Justice Ginsburg will continue to have periodic blood tests and scans. No further treatment is needed at this time.

 

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Last Fall, the Supreme Court Justice had surgery to remove two cancerous nodules in her lungs.

These were found a few weeks prior when she was undergoing treatment for a fall in which she sustained broken ribs on her left side.

The pulmonary lobectomy surgery occurred at Memorial Sloan Kettering Cancer Center in New York City as well.

Reportedly her current cancer does not appear to have spread to other parts of the body.

The 86-year-old Justice has previously battled colon cancer as well.

Each year over 56,000 Americans are diagnosed with pancreatic cancer, whose 5-year survival rate is 5%.  Older individuals who are healthy can do as well as those who are younger when diagnosed with advanced stage of the disease.  However some sources cite the median survival time is between 2 and 6 months if the cancer is diagnosed at a late stage.

This is a developing story.

 

ultimate book cover final

Great Gift!!!

The Ultimate Medical Student HandBook

 

Daliah Wachs, MD, FAAFP is a nationally syndicated radio personality on GCN Network, KDWN, and iHeart Radio.

Posted in cancer, Health, marijuana, news

Pot Found to Have Positive Effects on Pancreatic Cancer

A study out of Harvard found cannabis (the non-psychedelic component of marijuana) to decrease tumor size is mice afflicted with pancreatic cancer by 70%.

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The researchers from Dana-Farber Cancer Institute found a small chemical within cannabis called  FBL-0G3, also known as a flavanoid, a naturally occurring substance in many plants responsible for their vibrant color, and known for its antiiflammatory properties.

Marijuana Medical Benefits are Strain Specific

When mice with pancreatic cancer were given the FBL-0G3 along with radiation, their tumors shrank and in many, stopped growing.  The FBL-03G anticancer properties were also witnessed in a lab setting when combined with pancreatic cells in a petrie dish.

They conclude:

The findings demonstrate the potential for this new cannabis derivative in the treatment of both localized and advanced pancreatic cancer, providing impetus for further studies toward clinical translation.

Each year over 56,000 Americans are diagnosed with pancreatic cancer, whose 5-year survival rate is 5%.  Older individuals who are healthy can do as well as those who are younger when diagnosed with advanced stage of the disease.  However some sources cite the median survival time is between 2 and 6 months if the cancer is diagnosed at a late stage.

What are the risk factors for pancreatic cancer?

Known risk factors for pancreatic cancer include:

  • Older individuals
  • Male (though women are affected as well)
  • Diabetes
  • Alcohol use
  • Chronic pancreatitis
  • Genetics
  • African-American descent
  • Ashkenazi Jewish descent
  • Obesity
  • High fat diet
  • Hepatitis B
  • H. pylori infection
  • BRCA1 or BRCA2 mutations
    Can Diet Soda CAUSE Diabetes?

Artificial sweeteners have been linked to diabetes and diabetes is a risk factor for pancreatic cancer.  Their relationship to pancreatic cancer, however, still remains controversial.

 

ultimate book cover final

Great Gift!!!

The Ultimate Medical Student HandBook

 

Daliah Wachs, MD, FAAFP is a nationally syndicated radio personality on GCN Network, KDWN, and iHeart Radio.